Week 8 college football picks, games and odds: Ole Miss, Iowa State on alert

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After many weeks of banger clashes, things turn around in week 8, which is without a single ranked clash on the schedule. But sometimes the quieter Saturdays are the sneakiest. Oddly, however, there are a handful of clashes on the roster featuring ranked underdogs against unranked opponents.

Each week, potential upsets are selected based on favorable matches, context (ie. For maximum effect, a gap of at least three points is required for consideration – the larger, the better.

The week 7 picks were fair on the money with Oklahoma State beating Texas and UTEP overtaking Louisiana Tech; plus, Texas State and Vanderbilt covered. If it hadn’t been for the late heroism in these games, there could have been two more upheavals.

Important Disclaimer: “disrupt” is defined first and foremost by ratings, not ratings.

When: Saturday, 3:30 p.m. ET | Or: Oxford, Mississippi

Latest odds:

Ole Miss Rebels -9

So that no one will forget, Ed Orgeron is the greatest interim coach in the history of college football. OK – maybe that’s an exaggeration, but Coach O has a 12-4 record as an interim at USC and LSU. However, you want to dissect his tenure with the Tigers – Orgeron was fired last Sunday despite his win over Florida at home, but will coach the rest of the season – he seems to be doing his best when he’s back to the wall. It’s a little different, but the Tigers are playing with nothing to lose and have shown what they can accomplish against the Gators. Ole Miss looked fragile against Tennessee and still has significant defensive issues – can LSU take advantage of this? ATS: LSU, SU: Ole Miss

No. 8 State of Oklahoma to State of Iowa

When: Saturday, 3:30 p.m. ET | Or: Ames, Iowa

Latest odds:

Iowa State Cyclones -7

Can a team be both deeply overrated and deeply underrated? That’s what it feels like to see Oklahoma State as the No.8 team as an Iowa State touchdown underdog. The Cowboys beat three consecutive ranked teams to reach the top 10 AP, including the same Baylor team that beat Iowa State. Running back Jaylen Warren has become one of the best in the Big 12 to complete an elite defense. The Iowa State defense is also an elite, but the offense has been just as grueling despite the return of key production. Oklahoma State has found ways to win ugly games all year round. The ISU has always struggled in these places. TTY: State of Oklahoma, SU: State of Oklahoma

When: Saturday, 3 p.m. ET | Or: West Lafayette, Indiana

Latest odds:

Wisconsin Badgers -3

Purdue entered the standings for the first time since 2007, breaking college football’s longest unranked streak among the Power Five teams. Yet it was not enough for Boilermakers to earn the respect of bookmakers. At 4-2, Purdue is the underdog of a 3-3 placement in Wisconsin despite his ninth upset against a No. 2 in program history the week before (24-7 against Iowa). Purdue’s defense had four interceptions against quarterback Spencer Petras and Wisconsin starter Graham Mertz was even worse with two TDs to seven interceptions in six games. Yes, Wisconsin has one of the best defenses in college football, but wide receiver David Bell should still be seen as a cheat code after what he did against Iowa. ATS: Purdue, SU: Purdue

When: Saturday, 7 p.m. ET | Or: Colorado Springs, Colorado

Latest odds:

Air Force Falcons -3.5

The Aztecs needed a double overtime to beat defending champions MWC San Jose State, but they’re still 6-0 with a win over Utah getting better every week. The Air Force has had impressive back-to-back wins over Boise State and Wyoming, but the SDSU still has the sixth most effective defense in college football, according to SP +. Coach Brady Hoke’s iconic defensive line unit should be ready for the optional Air Force attack. TTY: San Diego State, SU: San Diego State

What college football picks can you confidently make in Week 8 and which top 10 team will be hit the hardest? Visit SportsLine to see which teams will win and cover the spread – all from a proven computer model that has grossed nearly $ 3,700 in profits over the past five+ seasons – and find out.


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